Metabolic regulation in the immune response to cancer
نویسندگان
چکیده
منابع مشابه
The metabolic response to cancer.
The syndrome of cachexia is characterized by anorexia and profound losses of host tissues and constitutes one of the most common paraneoplastic conditions seen with cancer. Furthermore, cachexia is associated with a considerable mortality and morbidity but its origin is still obscure and cachexia remains a multi-factorial problem. A better understanding of the cause of the cachectic process and...
متن کاملRegulation of the Immune Response
The kinetics of the in vivo response to SRBC was studied in mouse spleen at both the B cell and T cell levels. The B cell response was assayed by following the appearance of antibody-secreting cells in the spleen using the hemolytic plaque assay. The T cell response was monitored by following the increase in or "priming" of helper activity in the spleen using a quantitative in vitro assay. The ...
متن کاملRegulation of the Immune Response
The ability of 7S and F(ab')(2) antibody fragments to suppress priming with low doses of antigen was compared. The 7S preparation was approximately 100-1000 times more potent than the F(ab')(2) preparation when the agglutinin titers of the two preparations were the same. The presence of any ability to suppress priming in the F(ab')(2) preparation may reflect an inherent capacity of the F(ab')(2...
متن کاملRegulation of Immune Response to Virus
Acute murine lymphocytic choriomeningitis (LCM) ~ is a well documented example of predominantly cell-mediated immunopathology. The experimental evidence leading to this conclusion has been reviewed in extenso recently (1-3). The pathological process in vivo can be monitored in vitro by measuring LCM virus (LCMV)-specific cytotoxic activity of thymus-derived lymphocytes (T cells) for LCMV-infect...
متن کاملAntigen processing and immune regulation in the response to tumours.
The MHC class I and II antigen processing and presentation pathways display peptides to circulating CD8+ cytotoxic and CD4+ helper T cells respectively to enable pathogens and transformed cells to be identified. Once detected, T cells become activated and either directly kill the infected / transformed cells (CD8+ cytotoxic T lymphocytes) or orchestrate the activation of the adaptive immune res...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cancer Communications
سال: 2021
ISSN: 2523-3548,2523-3548
DOI: 10.1002/cac2.12182